3n1f: Difference between revisions

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{{Seed}}
[[Image:3n1f.png|left|200px]]
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{{STRUCTURE_3n1f|  PDB=3n1f  |  SCENE=  }}  
{{STRUCTURE_3n1f|  PDB=3n1f  |  SCENE=  }}  
===Crystal Structure of IhhN bound to CDOFn3===
===Crystal Structure of IhhN bound to CDOFn3===
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{{ABSTRACT_PUBMED_20519495}}
{{ABSTRACT_PUBMED_20519495}}


==Disease==
==Disease==
Known disease associated with this structure: Acrocapitofemoral dysplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600726 600726]], Brachydactyly, type A1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600726 600726]]
[[http://www.uniprot.org/uniprot/CDON_HUMAN CDON_HUMAN]] Defects in CDON are the cause of holoprosencephaly type 11 (HPE11) [MIM:[http://omim.org/entry/614226 614226]]. HPE11 is a structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.  
 
==Function==
[[http://www.uniprot.org/uniprot/CDON_HUMAN CDON_HUMAN]] Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity).


==About this Structure==
==About this Structure==
3N1F is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N1F OCA].  
[[3n1f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N1F OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20519495</ref><references group="xtra"/>
<ref group="xtra">PMID:020519495</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kavran, J M.]]
[[Category: Kavran, J M.]]
[[Category: Leahy, D J.]]
[[Category: Leahy, D J.]]
[[Category: Binding site]]
[[Category: Binding site]]
[[Category: Calcium]]
[[Category: Cell adhesion molecule]]
[[Category: Cell adhesion molecule]]
[[Category: Cell cycle protein]]
[[Category: Cell cycle protein]]
Line 48: Line 34:
[[Category: Tertiary]]
[[Category: Tertiary]]
[[Category: Tumor suppressor protein]]
[[Category: Tumor suppressor protein]]
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Retrieved from "https://proteopedia.org/3n1f"