2lqh: Difference between revisions

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[[Image:2lqh.jpg|left|200px]]
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{{STRUCTURE_2lqh|  PDB=2lqh  |  SCENE=  }}  
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===NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2b3l conformation)===
===NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2b3l conformation)===
{{ABSTRACT_PUBMED_22474372}}


 
==Function==
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[[http://www.uniprot.org/uniprot/CBP_MOUSE CBP_MOUSE]] Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300 (By similarity).<ref>PMID:10207073</ref><ref>PMID:11701890</ref><ref>PMID:15220471</ref><ref>PMID:16287980</ref>  
The line below this paragraph, {{ABSTRACT_PUBMED_22474372}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_22474372}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:022474372</ref><references group="xtra"/>
<ref group="xtra">PMID:022474372</ref><references group="xtra"/><references/>
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]