3l5w: Difference between revisions
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{{STRUCTURE_3l5w| PDB=3l5w | SCENE= }} | {{STRUCTURE_3l5w| PDB=3l5w | SCENE= }} | ||
===Crystal structure of the complex between IL-13 and C836 FAB=== | |||
{{ABSTRACT_PUBMED_20226193}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020226193</ref><references group="xtra"/> | <ref group="xtra">PMID:020226193</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
