1t2m: Difference between revisions
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{{STRUCTURE_1t2m| PDB=1t2m | SCENE= }} | {{STRUCTURE_1t2m| PDB=1t2m | SCENE= }} | ||
===Solution Structure Of The Pdz Domain Of AF-6=== | |||
{{ABSTRACT_PUBMED_15684424}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/AFAD_HUMAN AFAD_HUMAN]] Note=A chromosomal aberration involving MLLT4 is associated with acute leukemias. Translocation t(6;11)(q27;q23) with MLL/HRX. The result is a rogue activator protein. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/AFAD_HUMAN AFAD_HUMAN]] Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:015684424</ref><references group="xtra"/> | <ref group="xtra">PMID:015684424</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Huang, A D.]] | [[Category: Huang, A D.]] | ||
