1ugv: Difference between revisions
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{{STRUCTURE_1ugv| PDB=1ugv | SCENE= }} | {{STRUCTURE_1ugv| PDB=1ugv | SCENE= }} | ||
===Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/RHG26_HUMAN RHG26_HUMAN]] Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:[http://omim.org/entry/607785 607785]]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RHG26_HUMAN RHG26_HUMAN]] GTPase-activating protein for RHOA and CDC42. | |||
==About this Structure== | ==About this Structure== | ||
Revision as of 06:26, 25 March 2013
Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)
Disease
[RHG26_HUMAN] Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
Function
[RHG26_HUMAN] GTPase-activating protein for RHOA and CDC42.
About this Structure
1ugv is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Aoki, M.
- Hayashi, F.
- Hirota, H.
- Inoue, K.
- Inoue, M.
- Kigawa, T.
- Kikuno, R.
- Matsuda, T.
- Matsuo, Y.
- Nagase, T.
- Nakayama, M.
- Ohara, O.
- Osanai, T.
- RSGI, RIKEN Structural Genomics/Proteomics Initiative.
- Seki, E.
- Shirouzu, M.
- Tanaka, A.
- Terada, T.
- Yabuki, T.
- Yokoyama, S.
- Yoshida, M.
- Beta barrel
- Graf protein
- Protein binding
- Riken structural genomics/proteomics initiative
- Rsgi
- Structural genomic
