3mi2: Difference between revisions

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{{Seed}}
[[Image:3mi2.png|left|200px]]
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{{STRUCTURE_3mi2|  PDB=3mi2  |  SCENE=  }}  
{{STRUCTURE_3mi2|  PDB=3mi2  |  SCENE=  }}  
===Crystal structure of human orotidine-5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate===
===Crystal structure of human orotidine-5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate===
{{ABSTRACT_PUBMED_20452222}}


==Disease==
[[http://www.uniprot.org/uniprot/PYR5_HUMAN PYR5_HUMAN]] Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:[http://omim.org/entry/258900 258900]]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.<ref>PMID:9042911</ref>


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==About this Structure==
The line below this paragraph, {{ABSTRACT_PUBMED_20452222}}, adds the Publication Abstract to the page
[[3mi2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MI2 OCA].
(as it appears on PubMed at http://www.pubmed.gov), where 20452222 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20452222}}


==About this Structure==
==See Also==
3MI2 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MI2 OCA].
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20452222</ref><references group="xtra"/>
<ref group="xtra">PMID:020452222</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
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[[Category: Pyrazofurin monophosphate]]
[[Category: Pyrazofurin monophosphate]]
[[Category: Ump synthase]]
[[Category: Ump synthase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:14:36 2010''
Retrieved from "https://proteopedia.org/3mi2"