3ov6: Difference between revisions

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[[Image:3ov6.jpg|left|200px]]
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{{STRUCTURE_3ov6|  PDB=3ov6  |  SCENE=  }}  
{{STRUCTURE_3ov6|  PDB=3ov6  |  SCENE=  }}  
===CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide)===
===CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide)===
{{ABSTRACT_PUBMED_21167756}}


==Disease==
[[http://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN]] Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:[http://omim.org/entry/241600 241600]]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.<ref>PMID:16549777</ref>  Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.<ref>PMID:3532124</ref><ref>PMID:1336137</ref><ref>PMID:7554280</ref><ref>PMID:4586824</ref><ref>PMID:8084451</ref><ref>PMID:12119416</ref><ref>PMID:12796775</ref><ref>PMID:16901902</ref><ref>PMID:16491088</ref><ref>PMID:17646174</ref><ref>PMID:18835253</ref><ref>PMID:18395224</ref><ref>PMID:19284997</ref>


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_21167756}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.  
(as it appears on PubMed at http://www.pubmed.gov), where 21167756 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21167756}}


==About this Structure==
==About this Structure==
[[3ov6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OV6 OCA].  
[[3ov6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OV6 OCA].  
==See Also==
*[[Beta-2 microglobulin|Beta-2 microglobulin]]


==Reference==
==Reference==
<ref group="xtra">PMID:21167756</ref><references group="xtra"/>
<ref group="xtra">PMID:021167756</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Adams, E J.]]
[[Category: Adams, E J.]]
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[[Category: Shah, S.]]
[[Category: Shah, S.]]
[[Category: Zhang, T.]]
[[Category: Zhang, T.]]
[[Category: Antigen presentation]]
[[Category: Immune system]]
[[Category: Immunoglobulin domain]]
[[Category: Mhc]]
Retrieved from "https://proteopedia.org/3ov6"