4dy1: Difference between revisions
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{{STRUCTURE_4dy1| PDB=4dy1 | SCENE= }} | |||
===tRNA-guanine transglycosylase F92C C158S C281S mutant=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] | |||
==About this Structure== | |||
[[4dy1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DY1 OCA]. | |||
[[Category: Zymomonas mobilis]] | |||
[[Category: Heine, A.]] | |||
[[Category: Jakobi, S.]] | |||
[[Category: Klebe, G.]] | |||
[[Category: Functional dimer]] | |||
[[Category: Guanine binding]] | |||
[[Category: Guanine exchange enzyme]] | |||
[[Category: Protein-protein interface]] | |||
[[Category: Transferase]] | |||
[[Category: Trna binding]] | |||
[[Category: Zinc binding]] | |||
Revision as of 08:56, 27 March 2013
tRNA-guanine transglycosylase F92C C158S C281S mutant
Function
[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
About this Structure
4dy1 is a 1 chain structure with sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.
