4e01: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4e01|  PDB=4e01  |  SCENE=  }}
===Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with AMPPNP===


The entry 4e01 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/BCKD_RAT BCKD_RAT]] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.


Authors: Tso, S.C., Chuang, J.L., Gui, W.J., Wynn, R.M., Li, J., Chuang, D.T.
==About this Structure==
 
[[4e01]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E01 OCA].  
Description: Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with AMPPNP
[[Category: Rattus norvegicus]]
[[Category: Chuang, D T.]]
[[Category: Chuang, J L.]]
[[Category: Gui, W J.]]
[[Category: Li, J.]]
[[Category: Tso, S C.]]
[[Category: Wynn, R M.]]
[[Category: Allosteric kinase inhibitor]]
[[Category: Bergerat nucleotide-binding fold]]
[[Category: Branched-chain alpha-ketoacid]]
[[Category: Branched-chain amino acid]]
[[Category: Diabetes and obesity]]
[[Category: Ghkl protein kinase]]
[[Category: Maple syrup urine disease]]
[[Category: Protein kinase]]
[[Category: Transferase-transferase inhibitor complex]]