4e01: Difference between revisions
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{{STRUCTURE_4e01| PDB=4e01 | SCENE= }} | |||
===Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with AMPPNP=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/BCKD_RAT BCKD_RAT]] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. | |||
==About this Structure== | |||
[[4e01]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E01 OCA]. | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Chuang, D T.]] | |||
[[Category: Chuang, J L.]] | |||
[[Category: Gui, W J.]] | |||
[[Category: Li, J.]] | |||
[[Category: Tso, S C.]] | |||
[[Category: Wynn, R M.]] | |||
[[Category: Allosteric kinase inhibitor]] | |||
[[Category: Bergerat nucleotide-binding fold]] | |||
[[Category: Branched-chain alpha-ketoacid]] | |||
[[Category: Branched-chain amino acid]] | |||
[[Category: Diabetes and obesity]] | |||
[[Category: Ghkl protein kinase]] | |||
[[Category: Maple syrup urine disease]] | |||
[[Category: Protein kinase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||