4e2v: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4e2v|  PDB=4e2v  |  SCENE=  }}
===tRNA-guanine transglycosylase Y106F, C158V mutant in complex with preQ1===


The entry 4e2v is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]


Authors: Schmidt, I., Reuter, K., Klebe, G., Heine, A., Tidten, N.
==About this Structure==
 
[[4e2v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2V OCA].  
Description: tRNA-guanine transglycosylase Y106F, C158V mutant in complex with preQ1
[[Category: Zymomonas mobilis]]
[[Category: Heine, A.]]
[[Category: Klebe, G.]]
[[Category: Reuter, K.]]
[[Category: Schmidt, I.]]
[[Category: Tidten, N.]]
[[Category: Bacterial tgt]]
[[Category: Guanin]]
[[Category: Guanine exchange enzyme]]
[[Category: Preq1]]
[[Category: Substrate specificity]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Trna]]