4e2v: Difference between revisions
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{{STRUCTURE_4e2v| PDB=4e2v | SCENE= }} | |||
===tRNA-guanine transglycosylase Y106F, C158V mutant in complex with preQ1=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] | |||
==About this Structure== | |||
[[4e2v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2V OCA]. | |||
[[Category: Zymomonas mobilis]] | |||
[[Category: Heine, A.]] | |||
[[Category: Klebe, G.]] | |||
[[Category: Reuter, K.]] | |||
[[Category: Schmidt, I.]] | |||
[[Category: Tidten, N.]] | |||
[[Category: Bacterial tgt]] | |||
[[Category: Guanin]] | |||
[[Category: Guanine exchange enzyme]] | |||
[[Category: Preq1]] | |||
[[Category: Substrate specificity]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
[[Category: Trna]] | |||