3io3: Difference between revisions

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{{Seed}}
[[Image:3io3.jpg|left|200px]]
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The line below this paragraph, containing "STRUCTURE_3io3", creates the "Structure Box" on the page.
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{{STRUCTURE_3io3|  PDB=3io3  |  SCENE=  }}  
{{STRUCTURE_3io3|  PDB=3io3  |  SCENE=  }}  
===GEt3 with ADP from D. Hansenii in Closed form===
===GEt3 with ADP from D. Hansenii in Closed form===
{{ABSTRACT_PUBMED_19956640}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/GET3_DEBHA GET3_DEBHA]] ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity).
The line below this paragraph, {{ABSTRACT_PUBMED_19956640}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 19956640 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19956640}}


==About this Structure==
==About this Structure==
3IO3 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Debaryomyces_hansenii Debaryomyces hansenii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IO3 OCA].  
[[3io3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Debaryomyces_hansenii Debaryomyces hansenii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IO3 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19956640</ref><references group="xtra"/>
<ref group="xtra">PMID:019956640</ref><references group="xtra"/><references/>
[[Category: Debaryomyces hansenii]]
[[Category: Debaryomyces hansenii]]
[[Category: Hu, J.]]
[[Category: Hu, J.]]
Line 32: Line 19:
[[Category: Chaperone]]
[[Category: Chaperone]]
[[Category: Membrane traffic]]
[[Category: Membrane traffic]]
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Retrieved from "https://proteopedia.org/3io3"