3isj: Difference between revisions
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{{STRUCTURE_3isj| PDB=3isj | SCENE= }} | {{STRUCTURE_3isj| PDB=3isj | SCENE= }} | ||
===Crystal structure of pantothenate synthetase from Mycobacterium tuberculosis in complex with 5-methoxy-N-(methylsulfonyl)-1H-indole-2-carboxamide=== | ===Crystal structure of pantothenate synthetase from Mycobacterium tuberculosis in complex with 5-methoxy-N-(methylsulfonyl)-1H-indole-2-carboxamide=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3isj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ISJ OCA]. | |||
==See Also== | |||
*[[Pantothenate synthetase|Pantothenate synthetase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019780086</ref><references group="xtra"/><references/> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pantoate--beta-alanine ligase]] | [[Category: Pantoate--beta-alanine ligase]] | ||
| Line 27: | Line 22: | ||
[[Category: Wen, S.]] | [[Category: Wen, S.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Fragment-based drug design]] | [[Category: Fragment-based drug design]] | ||
[[Category: Ligase]] | [[Category: Ligase]] | ||
| Line 36: | Line 30: | ||
[[Category: Pantothenate biosynthesis]] | [[Category: Pantothenate biosynthesis]] | ||
[[Category: Pantothenate synthetase]] | [[Category: Pantothenate synthetase]] | ||
