3it5: Difference between revisions
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{{STRUCTURE_3it5| PDB=3it5 | SCENE= }} | {{STRUCTURE_3it5| PDB=3it5 | SCENE= }} | ||
===Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa=== | ===Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa=== | ||
{{ABSTRACT_PUBMED_20026068}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/LASA_PSEAE LASA_PSEAE]] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa. | |||
==About this Structure== | ==About this Structure== | ||
[[3it5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IT5 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020026068</ref><references group="xtra"/><references/> | ||
[[Category: Pseudomonas aeruginosa | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Conners, R.]] | [[Category: Conners, R.]] | ||
[[Category: Gamblin, S J.]] | [[Category: Gamblin, S J.]] | ||
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[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 09:36, 27 March 2013
Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa
Template:ABSTRACT PUBMED 20026068
Function
[LASA_PSEAE] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.
About this Structure
3it5 is a 4 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
Reference
- Spencer J, Murphy LM, Conners R, Sessions RB, Gamblin SJ. Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. J Mol Biol. 2010 Mar 5;396(4):908-23. Epub 2009 Dec 21. PMID:20026068 doi:10.1016/j.jmb.2009.12.021