2ymk: Difference between revisions
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{{STRUCTURE_2ymk| PDB=2ymk | SCENE= }} | {{STRUCTURE_2ymk| PDB=2ymk | SCENE= }} | ||
===Crystal structure of the hexameric anti-microbial peptide channel dermcidin=== | ===Crystal structure of the hexameric anti-microbial peptide channel dermcidin=== | ||
{{ABSTRACT_PUBMED_23426625}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DCD_HUMAN DCD_HUMAN]] DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.<ref>PMID:17448443</ref> Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.<ref>PMID:17448443</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2ymk]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YMK OCA]. | [[2ymk]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YMK OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Zeth, K.]] | [[Category: Zeth, K.]] | ||
[[Category: Anti-microbial peptide channel]] | [[Category: Anti-microbial peptide channel]] | ||
