3zpq: Difference between revisions
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{{STRUCTURE_3zpq| PDB=3zpq | SCENE= }} | |||
===Thermostabilised turkey beta1 adrenergic receptor with 4-(piperazin-1- yl)-1H-indole bound (compound 19)=== | |||
{{ABSTRACT_PUBMED_23517028}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA]] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. | |||
==About this Structure== | |||
[[3zpq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPQ OCA]. | |||
[[Category: Meleagris gallopavo]] | |||
[[Category: Brown, J.]] | |||
[[Category: Christopher, J A.]] | |||
[[Category: Congreve, M.]] | |||
[[Category: Dore, A S.]] | |||
[[Category: Errey, J C.]] | |||
[[Category: Koglin, M.]] | |||
[[Category: Marshall, F H.]] | |||
[[Category: Myszka, D G.]] | |||
[[Category: Tate, C G.]] | |||
[[Category: Tehan, B.]] | |||
[[Category: Warne, T.]] | |||
[[Category: Aryl piperazine]] | |||
[[Category: Fragment screening]] | |||
[[Category: Gpcr]] | |||
[[Category: Membrane protein]] | |||
[[Category: Structure based drug design]] | |||
Revision as of 01:35, 4 April 2013
Thermostabilised turkey beta1 adrenergic receptor with 4-(piperazin-1- yl)-1H-indole bound (compound 19)
Template:ABSTRACT PUBMED 23517028
Function
[ADRB1_MELGA] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
About this Structure
3zpq is a 2 chain structure with sequence from Meleagris gallopavo. Full crystallographic information is available from OCA.