4h11: Difference between revisions
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{{STRUCTURE_4h11| PDB=4h11 | SCENE= }} | |||
===Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy=== | |||
{{ABSTRACT_PUBMED_23519667}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DLG2_RAT DLG2_RAT]] Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity). | |||
==About this Structure== | |||
[[4h11]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H11 OCA]. | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Fiorentini, M.]] | |||
[[Category: Gajhede, M.]] | |||
[[Category: Kastrup, J S.]] | |||
[[Category: All beta pdz]] | |||
[[Category: Neuropeptide]] | |||
[[Category: Protein binding]] | |||
[[Category: Protein interaction]] | |||