3w3j: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3w3j|  PDB=3w3j  |  SCENE=  }}
===Crystal structure of human TLR8 in complex with CL097===
{{ABSTRACT_PUBMED_23520111}}


The entry 3w3j is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/TLR8_HUMAN TLR8_HUMAN]] Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:17932028</ref>  


Authors: Tanji, H., Ohto, U., Shimizu, T.
==About this Structure==
[[3w3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W3J OCA].  


Description: Crystal structure of human TLR8 in complex with CL097
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Ohto, U.]]
[[Category: Shimizu, T.]]
[[Category: Tanji, H.]]
[[Category: Cl097]]
[[Category: Glycosylation]]
[[Category: Immune system]]
[[Category: Innate immunity]]
[[Category: Leucine rich repeat]]
[[Category: Receptor]]
[[Category: Rna]]
[[Category: Rna binding]]
[[Category: Rna receptor]]
[[Category: Rna recognition]]
[[Category: Secreted]]
[[Category: Ssrna]]