3k9j: Difference between revisions

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{{Seed}}
[[Image:3k9j.png|left|200px]]
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{{STRUCTURE_3k9j|  PDB=3k9j  |  SCENE=  }}  
{{STRUCTURE_3k9j|  PDB=3k9j  |  SCENE=  }}  
===Transposase domain of Metnase===
===Transposase domain of Metnase===
{{ABSTRACT_PUBMED_20521842}}


 
==Function==
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[[http://www.uniprot.org/uniprot/SETMR_HUMAN SETMR_HUMAN]] Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA.<ref>PMID:16332963</ref> <ref>PMID:16672366</ref> <ref>PMID:17877369</ref> <ref>PMID:17403897</ref> 
The line below this paragraph, {{ABSTRACT_PUBMED_20521842}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 20521842 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20521842}}


==About this Structure==
==About this Structure==
3K9J is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K9J OCA].  
[[3k9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K9J OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20521842</ref><references group="xtra"/>
<ref group="xtra">PMID:020521842</ref><references group="xtra"/><references/>
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transposase]]
[[Category: Transposase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:48:53 2010''