3kl8: Difference between revisions
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{{STRUCTURE_3kl8| PDB=3kl8 | SCENE= }} | {{STRUCTURE_3kl8| PDB=3kl8 | SCENE= }} | ||
===CaMKIINtide Inhibitor Complex=== | ===CaMKIINtide Inhibitor Complex=== | ||
{{ABSTRACT_PUBMED_20139983}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q9U6Q0_CAEEL Q9U6Q0_CAEEL]] Role in locomotion and neuronal cell fate specification. Required for the regulation of synaptic density, egg laying, defecation, and meiotic maturation. Required for viability under chronic osmotic stress in which it acts downstream of osr-1. Regulates the synaptic trafficking of glr-1. Bidirectional modulator of neurotransmitter release with negative modulatory effects mainly mediated via slo-1 activation. May suppress the functional response to an internal pacemaker, perhaps by modulating the activity of the IP3 receptor.<ref>PMID:15166144</ref> <ref>PMID:16079277</ref> <ref>PMID:17898212</ref> <ref>PMID:17942636</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3kl8]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KL8 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020139983</ref><references group="xtra"/><references/> | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| Line 46: | Line 33: | ||
[[Category: Synaptosome]] | [[Category: Synaptosome]] | ||
[[Category: Transferase- transferase inhibitor complex]] | [[Category: Transferase- transferase inhibitor complex]] | ||