3k6t: Difference between revisions
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{{STRUCTURE_3k6t| PDB=3k6t | SCENE= }} | {{STRUCTURE_3k6t| PDB=3k6t | SCENE= }} | ||
===Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution=== | ===Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution=== | ||
{{ABSTRACT_PUBMED_20223220}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GLD1_CAEEL GLD1_CAEEL]] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation. | |||
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==About this Structure== | ==About this Structure== | ||
[[3k6t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6T OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020223220</ref><references group="xtra"/><references/> | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Beuck, C.]] | [[Category: Beuck, C.]] | ||
| Line 44: | Line 31: | ||
[[Category: Rna-binding]] | [[Category: Rna-binding]] | ||
[[Category: Translation regulation]] | [[Category: Translation regulation]] | ||