3k6t: Difference between revisions

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{{Seed}}
[[Image:3k6t.png|left|200px]]
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{{STRUCTURE_3k6t|  PDB=3k6t  |  SCENE=  }}  
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===Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution===
===Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution===
{{ABSTRACT_PUBMED_20223220}}


 
==Function==
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[[http://www.uniprot.org/uniprot/GLD1_CAEEL GLD1_CAEEL]] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation.
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{{ABSTRACT_PUBMED_20223220}}


==About this Structure==
==About this Structure==
3K6T is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6T OCA].  
[[3k6t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6T OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20223220</ref><references group="xtra"/>
<ref group="xtra">PMID:020223220</ref><references group="xtra"/><references/>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Beuck, C.]]
[[Category: Beuck, C.]]
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[[Category: Rna-binding]]
[[Category: Rna-binding]]
[[Category: Translation regulation]]
[[Category: Translation regulation]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 12:56:49 2010''