3ke8: Difference between revisions
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{{STRUCTURE_3ke8| PDB=3ke8 | SCENE= }} | {{STRUCTURE_3ke8| PDB=3ke8 | SCENE= }} | ||
===Crystal structure of IspH:HMBPP-complex=== | ===Crystal structure of IspH:HMBPP-complex=== | ||
{{ABSTRACT_PUBMED_020080550}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI]] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3ke8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KE8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:020080550</ref><references group="xtra"/><references/> | |||
[[Category: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase]] | [[Category: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: Groll, M.]] | [[Category: Groll, M.]] | ||
[[Category: Span, I.]] | [[Category: Span, I.]] | ||
[[Category: Fs4-iron-sulfure-cluster]] | [[Category: Fs4-iron-sulfure-cluster]] | ||
[[Category: Induced fit mechanism]] | [[Category: Induced fit mechanism]] | ||
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[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||