3k6l: Difference between revisions
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{{STRUCTURE_3k6l| PDB=3k6l | SCENE= }} | {{STRUCTURE_3k6l| PDB=3k6l | SCENE= }} | ||
===The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827=== | ===The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163] | |||
==About this Structure== | ==About this Structure== | ||
[[3k6l]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6L OCA]. | |||
[[Category: Escherichia coli k-12]] | [[Category: Escherichia coli k-12]] | ||
[[Category: Peptide deformylase]] | [[Category: Peptide deformylase]] | ||
| Line 23: | Line 15: | ||
[[Category: Whittaker, M.]] | [[Category: Whittaker, M.]] | ||
[[Category: Wood, M.]] | [[Category: Wood, M.]] | ||
[[Category: Hydrolase]] | |||
[[Category: Ion binding]] | [[Category: Ion binding]] | ||
[[Category: Iron]] | [[Category: Iron]] | ||
| Line 28: | Line 21: | ||
[[Category: Protein biosynthesis]] | [[Category: Protein biosynthesis]] | ||
[[Category: Translation]] | [[Category: Translation]] | ||
Revision as of 02:25, 4 April 2013
The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827
Function
[DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
About this Structure
3k6l is a 3 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
