3kfx: Difference between revisions
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{{STRUCTURE_3kfx| PDB=3kfx | SCENE= }} | {{STRUCTURE_3kfx| PDB=3kfx | SCENE= }} | ||
===Human dCK complex with 5-Me dC and ADP=== | ===Human dCK complex with 5-Me dC and ADP=== | ||
{{ABSTRACT_PUBMED_20614893}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DCK_HUMAN DCK_HUMAN]] Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.<ref>PMID:18377927</ref> <ref>PMID:20614893</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3kfx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFX OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020614893</ref><references group="xtra"/><references/> | ||
[[Category: Deoxycytidine kinase]] | [[Category: Deoxycytidine kinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||