3kem: Difference between revisions
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{{STRUCTURE_3kem| PDB=3kem | SCENE= }} | {{STRUCTURE_3kem| PDB=3kem | SCENE= }} | ||
===Crystal structure of IspH:IPP complex=== | ===Crystal structure of IspH:IPP complex=== | ||
{{ABSTRACT_PUBMED_020080550}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI]] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3kem]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEM OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:020080550</ref><references group="xtra"/><references/> | |||
[[Category: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase]] | [[Category: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: Groll, M.]] | [[Category: Groll, M.]] | ||
[[Category: Span, I.]] | [[Category: Span, I.]] | ||
[[Category: Iron]] | [[Category: Iron]] | ||
[[Category: Iron sulfure protein]] | [[Category: Iron sulfure protein]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Tuberculosis]] | [[Category: Tuberculosis]] | ||