3km8: Difference between revisions
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Revision as of 02:34, 4 April 2013
Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine
Function
[ADA_MOUSE] Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity).
About this Structure
3km8 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
