3k3r: Difference between revisions

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===Unrefined crystal structure of a LexA-DNA complex===

==Function==

[[http://www.uniprot.org/uniprot/LEXA_ECOLI LEXA_ECOLI]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.<ref>PMID:7027255</ref> <ref>PMID:7027256</ref>

==About this Structure==

~~3K3R~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K3R OCA].

[[3k3r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K3R OCA].

==Reference==

[[Category: Escherichia coli k-12]]

[[Category: Repressor lexA]]

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[[Category: Transcription regulation]]

[[Category: Winged helix-turn-helix]]

~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:42:25 2010''~~

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-{{Seed}}
-[[Image:3k3r.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3k3r", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3k3r|  PDB=3k3r  |  SCENE=  }}
 ===Unrefined crystal structure of a LexA-DNA complex===
+{{ABSTRACT_PUBMED_020703307}}
+==Function==
+[[http://www.uniprot.org/uniprot/LEXA_ECOLI LEXA_ECOLI]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.<ref>PMID:7027255</ref> <ref>PMID:7027256</ref>
 ==About this Structure==
-K3R is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K3R OCA].
+[[3k3r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K3R OCA].
+==Reference==
+<ref group="xtra">PMID:020703307</ref><references group="xtra"/><references/>
 [[Category: Escherichia coli k-12]]
 [[Category: Repressor lexA]]
@@ Line 36: / Line 32: @@
 [[Category: Transcription regulation]]
 [[Category: Winged helix-turn-helix]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:42:25 2010''