3kxt: Difference between revisions
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{{STRUCTURE_3kxt| PDB=3kxt | SCENE= }} | {{STRUCTURE_3kxt| PDB=3kxt | SCENE= }} | ||
===Crystal structure of Sulfolobus Cren7-dsDNA complex=== | ===Crystal structure of Sulfolobus Cren7-dsDNA complex=== | ||
{{ABSTRACT_PUBMED_20512977}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CREN7_SULSO CREN7_SULSO]] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.<ref>PMID:18096617</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3kxt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXT OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020512977</ref><references group="xtra"/><references/> | ||
[[Category: Sulfolobus solfataricus]] | [[Category: Sulfolobus solfataricus]] | ||
[[Category: Feng, Y.]] | [[Category: Feng, Y.]] | ||
| Line 32: | Line 19: | ||
[[Category: Minor-groove binding]] | [[Category: Minor-groove binding]] | ||
[[Category: Protein-dna complex]] | [[Category: Protein-dna complex]] | ||
Revision as of 20:03, 4 April 2013
Crystal structure of Sulfolobus Cren7-dsDNA complex
Template:ABSTRACT PUBMED 20512977
Function
[CREN7_SULSO] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.[1]
About this Structure
3kxt is a 3 chain structure with sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.
Reference
- Feng Y, Yao H, Wang J. Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex. Protein Sci. 2010 Jun;19(6):1253-7. PMID:20512977 doi:10.1002/pro.385
- ↑ Guo L, Feng Y, Zhang Z, Yao H, Luo Y, Wang J, Huang L. Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea. Nucleic Acids Res. 2008 Mar;36(4):1129-37. Epub 2007 Dec 20. PMID:18096617 doi:10.1093/nar/gkm1128
