3kvv: Difference between revisions
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{{STRUCTURE_3kvv| PDB=3kvv | SCENE= }} | {{STRUCTURE_3kvv| PDB=3kvv | SCENE= }} | ||
===Trapping of an oxocarbenium ion intermediate in UP crystals=== | ===Trapping of an oxocarbenium ion intermediate in UP crystals=== | ||
{{ABSTRACT_PUBMED_20364833}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/UDP_ECOLI UDP_ECOLI]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | |||
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==About this Structure== | ==About this Structure== | ||
[[3kvv]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KVV OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020364833</ref><references group="xtra"/><references/> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Uridine phosphorylase]] | [[Category: Uridine phosphorylase]] | ||
| Line 35: | Line 22: | ||
[[Category: Settembre, E.]] | [[Category: Settembre, E.]] | ||
[[Category: Toms, A.]] | [[Category: Toms, A.]] | ||
[[Category: Glycal]] | [[Category: Glycal]] | ||
[[Category: Glycosyltransferase]] | [[Category: Glycosyltransferase]] | ||
| Line 42: | Line 28: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Uridine phosphorylase]] | [[Category: Uridine phosphorylase]] | ||
Revision as of 20:07, 4 April 2013
Trapping of an oxocarbenium ion intermediate in UP crystals
Template:ABSTRACT PUBMED 20364833
Function
[UDP_ECOLI] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
About this Structure
3kvv is a 6 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Paul D, O'Leary SE, Rajashankar K, Bu W, Toms A, Settembre EC, Sanders JM, Begley TP, Ealick SE. Glycal formation in crystals of uridine phosphorylase. Biochemistry. 2010 Apr 27;49(16):3499-509. PMID:20364833 doi:10.1021/bi902073b
