3lcc: Difference between revisions
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{{STRUCTURE_3lcc| PDB=3lcc | SCENE= }} | {{STRUCTURE_3lcc| PDB=3lcc | SCENE= }} | ||
===Structure of a SAM-dependent halide methyltransferase from Arabidopsis thaliana=== | ===Structure of a SAM-dependent halide methyltransferase from Arabidopsis thaliana=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/HOL1_ARATH HOL1_ARATH]] S-adenosyl-L-methionine-dependent methyltransferase. Involved in glucosinolate metabolism and defense against phytopathogens. Highly reactive to thiocyanate (NCS(-)) derived from myrosinase-mediated hydrolysis of glucosinolates upon tissue damage.[REFERENCE:8]<ref>PMID:19419967</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3lcc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCC OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020376845</ref><references group="xtra"/><references/> | ||
[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
[[Category: Hagan, D O.]] | [[Category: Hagan, D O.]] | ||
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[[Category: Halide methyltransferase]] | [[Category: Halide methyltransferase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 20:13, 4 April 2013
Structure of a SAM-dependent halide methyltransferase from Arabidopsis thaliana
Function
[HOL1_ARATH] S-adenosyl-L-methionine-dependent methyltransferase. Involved in glucosinolate metabolism and defense against phytopathogens. Highly reactive to thiocyanate (NCS(-)) derived from myrosinase-mediated hydrolysis of glucosinolates upon tissue damage.[REFERENCE:8][1]
About this Structure
3lcc is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
- Schmidberger JW, James AB, Edwards R, Naismith JH, O'Hagan D. Halomethane biosynthesis: structure of a SAM-dependent halide methyltransferase from Arabidopsis thaliana. Angew Chem Int Ed Engl. 2010 May 10;49(21):3646-8. PMID:20376845 doi:10.1002/anie.201000119
- ↑ Nagatoshi Y, Nakamura T. Arabidopsis HARMLESS TO OZONE LAYER protein methylates a glucosinolate breakdown product and functions in resistance to Pseudomonas syringae pv. maculicola. J Biol Chem. 2009 Jul 17;284(29):19301-9. doi: 10.1074/jbc.M109.001032. Epub 2009, May 6. PMID:19419967 doi:10.1074/jbc.M109.001032
