3lkm: Difference between revisions
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{{STRUCTURE_3lkm| PDB=3lkm | SCENE= }} | {{STRUCTURE_3lkm| PDB=3lkm | SCENE= }} | ||
===1.6 Angstrom Crystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex with AMP=== | ===1.6 Angstrom Crystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex with AMP=== | ||
{{ABSTRACT_PUBMED_20197546}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MHCKA_DICDI MHCKA_DICDI]] Phosphorylates threonine in the C-terminal tail region of myosin II heavy chain. This phosphorylation is critical in regulating the assembly and disassembly of myosin II filament. Requires autophosphorylation for activity. | |||
==About this Structure== | ==About this Structure== | ||
[[3lkm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LKM OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020197546</ref><references group="xtra"/><references/> | ||
[[Category: Dictyostelium discoideum]] | [[Category: Dictyostelium discoideum]] | ||
[[Category: Jia, Z.]] | [[Category: Jia, Z.]] | ||
| Line 29: | Line 16: | ||
[[Category: Alpha-kinase]] | [[Category: Alpha-kinase]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
| Line 36: | Line 22: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Wd repeat]] | [[Category: Wd repeat]] | ||
Revision as of 20:19, 4 April 2013
1.6 Angstrom Crystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex with AMP
Template:ABSTRACT PUBMED 20197546
Function
[MHCKA_DICDI] Phosphorylates threonine in the C-terminal tail region of myosin II heavy chain. This phosphorylation is critical in regulating the assembly and disassembly of myosin II filament. Requires autophosphorylation for activity.
About this Structure
3lkm is a 1 chain structure with sequence from Dictyostelium discoideum. Full crystallographic information is available from OCA.
Reference
- Ye Q, Crawley SW, Yang Y, Cote GP, Jia Z. Crystal structure of the alpha-kinase domain of Dictyostelium myosin heavy chain kinase A. Sci Signal. 2010 Mar 2;3(111):ra17. PMID:20197546 doi:3/111/ra17