3l94: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
m Protected "3l94" [edit=sysop:move=sysop]
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:3l94.jpg|left|200px]]
<!--
The line below this paragraph, containing "STRUCTURE_3l94", creates the "Structure Box" on the page.
You may change the PDB parameter (which sets the PDB file loaded into the applet)
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
or leave the SCENE parameter empty for the default display.
-->
{{STRUCTURE_3l94|  PDB=3l94  |  SCENE=  }}  
{{STRUCTURE_3l94|  PDB=3l94  |  SCENE=  }}  
===Structure of PvdQ covalently acylated with myristate===
===Structure of PvdQ covalently acylated with myristate===


==Function==
[[http://www.uniprot.org/uniprot/PVDQ_PSEAE PVDQ_PSEAE]] Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length). Degrades 3-oxo-C12-HSL, one of the two main AHL signal molecules of P.aeruginosa, and thereby functions as a quorum quencher, inhibiting the las quorum-sensing system. Therefore, may enable P.aeruginosa to modulate its own quorum-sensing-dependent pathogenic potential. Also appears to be required for pyoverdin biosynthesis.<ref>PMID:16495538</ref> <ref>PMID:14532048</ref> <ref>PMID:12686626</ref> 


==About this Structure==
==About this Structure==
[[3l94]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L94 OCA].  
[[3l94]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L94 OCA].  
==Reference==
<references group="xtra"/><references/>
[[Category: Acyl-homoserine-lactone acylase]]
[[Category: Acyl-homoserine-lactone acylase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Drake, E J.]]
[[Category: Drake, E J.]]
[[Category: Gulick, A M.]]
[[Category: Gulick, A M.]]
[[Category: Acylase]]
[[Category: Hydrolase]]
[[Category: Ntn hydrolase]]
[[Category: Pvdq]]
[[Category: Pyoverdine]]
[[Category: Quorum sensing]]
[[Category: Zymogen]]