3lgd: Difference between revisions
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{{STRUCTURE_3lgd| PDB=3lgd | SCENE= }} | {{STRUCTURE_3lgd| PDB=3lgd | SCENE= }} | ||
===Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2)=== | ===Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2)=== | ||
{{ABSTRACT_PUBMED_20147294}} | |||
==Disease== | |||
[[http://www.uniprot.org/uniprot/CECR1_HUMAN CECR1_HUMAN]] Cat-eye syndrome. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CECR1_HUMAN CECR1_HUMAN]] Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity.<ref>PMID:20453107</ref> <ref>PMID:20147294</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3lgd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LGD OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020147294</ref><references group="xtra"/><references/> | ||
[[Category: Adenosine deaminase]] | [[Category: Adenosine deaminase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Tim barrel]] | [[Category: Tim barrel]] | ||