3ljc: Difference between revisions

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{{Seed}}
[[Image:3ljc.png|left|200px]]
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The line below this paragraph, containing "STRUCTURE_3ljc", creates the "Structure Box" on the page.
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{{STRUCTURE_3ljc|  PDB=3ljc  |  SCENE=  }}  
{{STRUCTURE_3ljc|  PDB=3ljc  |  SCENE=  }}  
===Crystal structure of Lon N-terminal domain.===
===Crystal structure of Lon N-terminal domain.===
{{ABSTRACT_PUBMED_20693685}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/LON_ECOLI LON_ECOLI]] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins, including some antitoxins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system.<ref>PMID:12135363</ref> <ref>PMID:16584195</ref> <ref>PMID:19721064</ref> 
The line below this paragraph, {{ABSTRACT_PUBMED_20693685}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 20693685 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20693685}}


==About this Structure==
==About this Structure==
3LJC is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJC OCA].  
[[3ljc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJC OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20693685</ref><references group="xtra"/>
<ref group="xtra">PMID:020693685</ref><references group="xtra"/><references/>
[[Category: Endopeptidase La]]
[[Category: Endopeptidase La]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
Line 39: Line 26:
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Stress response]]
[[Category: Stress response]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:17:36 2010''
Retrieved from "https://proteopedia.org/3ljc"