3lda: Difference between revisions

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[[Image:3lda.png|left|200px]]
<!--
The line below this paragraph, containing "STRUCTURE_3lda", creates the "Structure Box" on the page.
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{{STRUCTURE_3lda|  PDB=3lda  |  SCENE=  }}  
{{STRUCTURE_3lda|  PDB=3lda  |  SCENE=  }}  
===Yeast Rad51 H352Y Filament Interface Mutant===
===Yeast Rad51 H352Y Filament Interface Mutant===
{{ABSTRACT_PUBMED_20371520}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/RAD51_YEAST RAD51_YEAST]] Required both for recombination and for the repair of DNA damage caused by X-rays. Its function may be modulated by interaction with other repair proteins. RAD52 interacts directly with RAD51, via its C-terminus. Forms a nucleoprotein filament with DNA as an early intermediate in recombination.<ref>PMID:16818607</ref>
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{{ABSTRACT_PUBMED_20371520}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:20371520</ref><references group="xtra"/>
<ref group="xtra">PMID:020371520</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chen, J.]]
[[Category: Chen, J.]]

Revision as of 20:30, 4 April 2013

Template:STRUCTURE 3lda

Yeast Rad51 H352Y Filament Interface Mutant

Template:ABSTRACT PUBMED 20371520

Function

[RAD51_YEAST] Required both for recombination and for the repair of DNA damage caused by X-rays. Its function may be modulated by interaction with other repair proteins. RAD52 interacts directly with RAD51, via its C-terminus. Forms a nucleoprotein filament with DNA as an early intermediate in recombination.[1]

About this Structure

3lda is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  1. Chen J, Villanueva N, Rould MA, Morrical SW. Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant. Nucleic Acids Res. 2010 Aug;38(14):4889-906. Epub 2010 Apr 5. PMID:20371520 doi:10.1093/nar/gkq209
  1. ↑ Tsubouchi H, Roeder GS. Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. Genes Dev. 2006 Jul 1;20(13):1766-75. PMID:16818607 doi:20/13/1766

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