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Protein Z


Table of Contents
== Protein Z ==


Background
 
'''Table of Contents'''
 
'''Background'''


Protein Z (PZ) is a vitamin k-dependent glycoprotein made in the liver and involved in the coagulation cascade. Bovine PZ was first identified by Prowse and Esnouf in 1977 and Human PZ was first isolated and studied by Broze Jr. and Miletich in 1984. The gene coding for PZ, called PROZ, was found in 1998 on chromosome 13 at location 13q34 and is composed of nine exons (one being an alternative exon).  
Protein Z (PZ) is a vitamin k-dependent glycoprotein made in the liver and involved in the coagulation cascade. Bovine PZ was first identified by Prowse and Esnouf in 1977 and Human PZ was first isolated and studied by Broze Jr. and Miletich in 1984. The gene coding for PZ, called PROZ, was found in 1998 on chromosome 13 at location 13q34 and is composed of nine exons (one being an alternative exon).  


Structure
'''Structure'''


Function
'''Function'''


Clinical Relevance  
'''Clinical Relevance'''


References
'''References'''