4gmj: Difference between revisions
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{{STRUCTURE_4gmj| PDB=4gmj | SCENE= }} | {{STRUCTURE_4gmj| PDB=4gmj | SCENE= }} | ||
===Structure of human NOT1 MIF4G domain co-crystallized with CAF1=== | ===Structure of human NOT1 MIF4G domain co-crystallized with CAF1=== | ||
{{ABSTRACT_PUBMED_22977175}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CNOT1_HUMAN CNOT1_HUMAN]] Belongs to the CCR4-NOT complex that functions as general transcription regulation complex. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors.<ref>PMID:10637334</ref> <ref>PMID:16778766</ref> [[http://www.uniprot.org/uniprot/CNOT7_HUMAN CNOT7_HUMAN]] Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
[[4gmj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMJ OCA]. | [[4gmj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMJ OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Izaurralde, E]] | [[Category: Izaurralde, E.]] | ||
[[Category: Petit, P]] | [[Category: Petit, P.]] | ||
[[Category: Weichenrieder, O]] | [[Category: Weichenrieder, O.]] | ||
[[Category: Wohlbold, L]] | [[Category: Wohlbold, L.]] | ||
[[Category: Ccr4-not]] | [[Category: Ccr4-not]] | ||
[[Category: Deadenylase]] | [[Category: Deadenylase]] | ||
