4j3o: Difference between revisions
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{{STRUCTURE_4j3o| PDB=4j3o | SCENE= }} | |||
===Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FIMF_ECOLI FIMF_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMG_ECOLI FIMG_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMC_ECOLI FIMC_ECOLI]] Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH. [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. [[http://www.uniprot.org/uniprot/FIMD_ECOLI FIMD_ECOLI]] Involved in the export and assembly of FimA fimbrial subunits across the outer membrane. | |||
==About this Structure== | |||
[[4j3o]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Gekko coi]] | |||
[[Category: Geibel, S.]] | |||
[[Category: Waksman, G.]] | |||
[[Category: Adhesion]] | |||
[[Category: Bacterial outer membrane]] | |||
[[Category: Beta barrel]] | |||
[[Category: Cell adhesion-chaperone-membrane protein complex]] | |||
[[Category: D-mannose-binding]] | |||
[[Category: Immunglobuline-like fold]] | |||
[[Category: Pilus subunit translocation]] | |||
[[Category: Type 1 pilus assembly]] | |||