3mex: Difference between revisions
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{{STRUCTURE_3mex| PDB=3mex | SCENE= }} | {{STRUCTURE_3mex| PDB=3mex | SCENE= }} | ||
===Crystal structure of MexR in oxidized state=== | ===Crystal structure of MexR in oxidized state=== | ||
{{ABSTRACT_PUBMED_20616806}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MEXR_PSEAE MEXR_PSEAE]] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon. | |||
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==About this Structure== | ==About this Structure== | ||
[[3mex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEX OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020616806</ref><references group="xtra"/><references/> | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Chen, H.]] | [[Category: Chen, H.]] | ||
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[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
Revision as of 23:02, 10 April 2013
Crystal structure of MexR in oxidized state
Template:ABSTRACT PUBMED 20616806
Function
[MEXR_PSEAE] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon.
About this Structure
3mex is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
Reference
- Chen H, Yi C, Zhang J, Zhang W, Ge Z, Yang CG, He C. Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR. EMBO Rep. 2010 Sep;11(9):685-90. Epub 2010 Jul 9. PMID:20616806 doi:10.1038/embor.2010.96