3m66: Difference between revisions

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{{Seed}}
[[Image:3m66.png|left|200px]]
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{{STRUCTURE_3m66|  PDB=3m66  |  SCENE=  }}  
{{STRUCTURE_3m66|  PDB=3m66  |  SCENE=  }}  
===Crystal structure of human Mitochondrial Transcription Termination Factor 3===
===Crystal structure of human Mitochondrial Transcription Termination Factor 3===
{{ABSTRACT_PUBMED_20430012}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/MTER1_HUMAN MTER1_HUMAN]] Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).<ref>PMID:17662942</ref>
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{{ABSTRACT_PUBMED_20430012}}


==About this Structure==
==About this Structure==
3M66 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M66 OCA].  
[[3m66]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M66 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20430012</ref><references group="xtra"/>
<ref group="xtra">PMID:020430012</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Gustafsson, C M.]]
[[Category: Gustafsson, C M.]]
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[[Category: Transcription termination]]
[[Category: Transcription termination]]
[[Category: Transit peptide]]
[[Category: Transit peptide]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:29:35 2010''

Revision as of 23:03, 10 April 2013

Template:STRUCTURE 3m66

Crystal structure of human Mitochondrial Transcription Termination Factor 3

Template:ABSTRACT PUBMED 20430012

Function

[MTER1_HUMAN] Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).[1]

About this Structure

3m66 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Spahr H, Samuelsson T, Hallberg BM, Gustafsson CM. Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain. Biochem Biophys Res Commun. 2010 Jul 2;397(3):386-90. Epub 2010 Apr 27. PMID:20430012 doi:10.1016/j.bbrc.2010.04.130
  1. ↑ Park CB, Asin-Cayuela J, Camara Y, Shi Y, Pellegrini M, Gaspari M, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Falkenberg M, Gustafsson CM, Larsson NG. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell. 2007 Jul 27;130(2):273-85. PMID:17662942 doi:10.1016/j.cell.2007.05.046

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