3lre: Difference between revisions
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{{STRUCTURE_3lre| PDB=3lre | SCENE= }} | {{STRUCTURE_3lre| PDB=3lre | SCENE= }} | ||
===Crystal Structure Analysis of Human Kinesin-8 Motor Domain=== | ===Crystal Structure Analysis of Human Kinesin-8 Motor Domain=== | ||
{{ABSTRACT_PUBMED_20818331}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KI18A_HUMAN KI18A_HUMAN]] Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.<ref>PMID:17346968</ref> <ref>PMID:18267093</ref> <ref>PMID:18513970</ref> <ref>PMID:19625775</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3lre]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LRE OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020818331</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Brejc, K.]] | [[Category: Brejc, K.]] | ||
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[[Category: Protein transport]] | [[Category: Protein transport]] | ||
[[Category: Transport]] | [[Category: Transport]] | ||