3lms: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3lms| PDB=3lms | SCENE= }} | {{STRUCTURE_3lms| PDB=3lms | SCENE= }} | ||
===Structure of human activated thrombin-activatable fibrinolysis inhibitor, TAFIa, in complex with tick-derived funnelin inhibitor, TCI.=== | ===Structure of human activated thrombin-activatable fibrinolysis inhibitor, TAFIa, in complex with tick-derived funnelin inhibitor, TCI.=== | ||
{{ABSTRACT_PUBMED_20088943}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CBPB2_HUMAN CBPB2_HUMAN]] Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.<ref>PMID:10574983</ref> | |||
--> | |||
==About this Structure== | ==About this Structure== | ||
[[3lms]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rhipicephalus_bursa Rhipicephalus bursa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LMS OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020088943</ref><references group="xtra"/><references/> | ||
[[Category: Carboxypeptidase U]] | [[Category: Carboxypeptidase U]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 34: | Line 21: | ||
[[Category: Valnickova, Z.]] | [[Category: Valnickova, Z.]] | ||
[[Category: Alpha-beta-hydrolase]] | [[Category: Alpha-beta-hydrolase]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Carboxypeptidase]] | [[Category: Carboxypeptidase]] | ||
| Line 49: | Line 35: | ||
[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Metalloprotease inhibitor]] | [[Category: Metalloprotease inhibitor]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||