2c8f: Difference between revisions
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{{STRUCTURE_2c8f| PDB=2c8f | SCENE= }} | {{STRUCTURE_2c8f| PDB=2c8f | SCENE= }} | ||
===STRUCTURE OF THE ARTT MOTIF E214N MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM III)=== | ===STRUCTURE OF THE ARTT MOTIF E214N MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM III)=== | ||
{{ABSTRACT_PUBMED_18369192}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ARC3_CBDP ARC3_CBDP]] ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018369192</ref><ref group="xtra">PMID:012029083</ref><references group="xtra"/> | <ref group="xtra">PMID:018369192</ref><ref group="xtra">PMID:012029083</ref><references group="xtra"/><references/> | ||
[[Category: Clostridium botulinum]] | [[Category: Clostridium botulinum]] | ||
[[Category: Boquet, P.]] | [[Category: Boquet, P.]] | ||
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[[Category: Menez, A.]] | [[Category: Menez, A.]] | ||
[[Category: Stura, E A.]] | [[Category: Stura, E A.]] | ||
[[Category: Artt motif]] | |||
[[Category: Bacterial toxin]] | |||
[[Category: C3 exoenzyme]] | |||
[[Category: Glycosyltransferase]] | |||
[[Category: Transferase]] | |||
Revision as of 23:22, 10 April 2013
STRUCTURE OF THE ARTT MOTIF E214N MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM III)
Template:ABSTRACT PUBMED 18369192
Function
[ARC3_CBDP] ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue.
About this Structure
2c8f is a 3 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.
Reference
- Menetrey J, Flatau G, Boquet P, Menez A, Stura EA. Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes. Protein Sci. 2008 May;17(5):878-86. Epub 2008 Mar 27. PMID:18369192 doi:10.1110/ps.073398508
- Menetrey J, Flatau G, Stura EA, Charbonnier JB, Gas F, Teulon JM, Le Du MH, Boquet P, Menez A. NAD binding induces conformational changes in Rho ADP-ribosylating clostridium botulinum C3 exoenzyme. J Biol Chem. 2002 Aug 23;277(34):30950-7. Epub 2002 May 23. PMID:12029083 doi:10.1074/jbc.M201844200