3lwi: Difference between revisions

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{{Seed}}
[[Image:3lwi.jpg|left|200px]]
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{{STRUCTURE_3lwi|  PDB=3lwi  |  SCENE=  }}  
{{STRUCTURE_3lwi|  PDB=3lwi  |  SCENE=  }}  
===Crystal structure of Cren7-dsDNA complex===
===Crystal structure of Cren7-dsDNA complex===
{{ABSTRACT_PUBMED_20345658}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/CREN7_SULSO CREN7_SULSO]] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.<ref>PMID:18096617</ref>
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{{ABSTRACT_PUBMED_20345658}}


==About this Structure==
==About this Structure==
3LWI is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LWI OCA].  
[[3lwi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LWI OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20345658</ref><references group="xtra"/>
<ref group="xtra">PMID:020345658</ref><references group="xtra"/><references/>
[[Category: Sulfolobus solfataricus]]
[[Category: Sulfolobus solfataricus]]
[[Category: Gong, Y.]]
[[Category: Gong, Y.]]
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[[Category: Methylation]]
[[Category: Methylation]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:33:52 2010''

Revision as of 23:28, 10 April 2013

Template:STRUCTURE 3lwi

Crystal structure of Cren7-dsDNA complex

Template:ABSTRACT PUBMED 20345658

Function

[CREN7_SULSO] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.[1]

About this Structure

3lwi is a 6 chain structure with sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

  1. Zhang Z, Gong Y, Guo L, Jiang T, Huang L. Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA. Mol Microbiol. 2010 May;76(3):749-59. Epub 2010 Mar 16. PMID:20345658 doi:10.1111/j.1365-2958.2010.07136.x
  1. ↑ Guo L, Feng Y, Zhang Z, Yao H, Luo Y, Wang J, Huang L. Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea. Nucleic Acids Res. 2008 Mar;36(4):1129-37. Epub 2007 Dec 20. PMID:18096617 doi:10.1093/nar/gkm1128

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