3mdi: Difference between revisions

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{{Seed}}
[[Image:3mdi.png|left|200px]]
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{{STRUCTURE_3mdi|  PDB=3mdi  |  SCENE=  }}  
{{STRUCTURE_3mdi|  PDB=3mdi  |  SCENE=  }}  
===Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im in complex with RNA UGUAAA===
===Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im in complex with RNA UGUAAA===
{{ABSTRACT_PUBMED_20479262}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/CPSF5_HUMAN CPSF5_HUMAN]] Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:20479262</ref> <ref>PMID:21295486</ref> 
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{{ABSTRACT_PUBMED_20479262}}


==About this Structure==
==About this Structure==
3MDI is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDI OCA].  
[[3mdi]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDI OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20479262</ref><references group="xtra"/>
<ref group="xtra">PMID:020479262</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Doublie, S.]]
[[Category: Doublie, S.]]
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[[Category: Rna binding protein]]
[[Category: Rna binding protein]]
[[Category: Rna binding-rna complex]]
[[Category: Rna binding-rna complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:11:29 2010''
Retrieved from "https://proteopedia.org/3mdi"