2vwi: Difference between revisions
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{{STRUCTURE_2vwi| PDB=2vwi | SCENE= }} | {{STRUCTURE_2vwi| PDB=2vwi | SCENE= }} | ||
===Structure of the OSR1 kinase, a hypertension drug target=== | |||
== | ==Function== | ||
[[http://www.uniprot.org/uniprot/OXSR1_HUMAN OXSR1_HUMAN]] Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.<ref>PMID:14707132</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2vwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VWI OCA]. | [[2vwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VWI OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Alessi, D R.]] | [[Category: Alessi, D R.]] | ||
[[Category: Deak, M.]] | [[Category: Deak, M.]] | ||
[[Category: Villa, F.]] | [[Category: Villa, F.]] | ||
[[Category: VanAalten, D M.F.]] | |||
[[Category: Hypertension]] | [[Category: Hypertension]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Ste kinase]] | [[Category: Ste kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 19:11, 17 April 2013
Structure of the OSR1 kinase, a hypertension drug target
Function
[OXSR1_HUMAN] Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.[1]
About this Structure
2vwi is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Chen W, Yazicioglu M, Cobb MH. Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily. J Biol Chem. 2004 Mar 19;279(12):11129-36. Epub 2004 Jan 5. PMID:14707132 doi:10.1074/jbc.M313562200
