3zn3: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "3zn3" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3zn3| PDB=3zn3 | SCENE= }} | {{STRUCTURE_3zn3| PDB=3zn3 | SCENE= }} | ||
===N-terminal domain of S. pombe Cdc23 APC subunit=== | ===N-terminal domain of S. pombe Cdc23 APC subunit=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/APC8_SCHPO APC8_SCHPO]] Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Has a role in promoting metaphase to anaphase transition via the ubiquitination of specific mitotic substrates.<ref>PMID:10526233</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3zn3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZN3 OCA]. | [[3zn3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZN3 OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Schizosaccharomyces pombe]] | [[Category: Schizosaccharomyces pombe]] | ||
[[Category: Barford, D.]] | [[Category: Barford, D.]] | ||
