4fzf: Difference between revisions
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{{STRUCTURE_4fzf| PDB=4fzf | SCENE= }} | {{STRUCTURE_4fzf| PDB=4fzf | SCENE= }} | ||
===Crystal structure of MST4-MO25 complex with DKI=== | ===Crystal structure of MST4-MO25 complex with DKI=== | ||
{{ABSTRACT_PUBMED_23434407}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CAB39_HUMAN CAB39_HUMAN]] Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1. [[http://www.uniprot.org/uniprot/MST4_HUMAN MST4_HUMAN]] Mediator of cell growth. Modulates apoptosis.<ref>PMID:17360971</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[4fzf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FZF OCA]. | [[4fzf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FZF OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
Revision as of 19:27, 17 April 2013
Crystal structure of MST4-MO25 complex with DKI
Template:ABSTRACT PUBMED 23434407
Function
[CAB39_HUMAN] Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1. [MST4_HUMAN] Mediator of cell growth. Modulates apoptosis.[1]
About this Structure
4fzf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Ma X, Zhao H, Shan J, Long F, Chen Y, Chen Y, Zhang Y, Han X, Ma D. PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway. Mol Biol Cell. 2007 Jun;18(6):1965-78. Epub 2007 Mar 14. PMID:17360971 doi:10.1091/mbc.E06-07-0608
