4da5: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4da5|  PDB=4da5  |  SCENE=  }}
===Choline Kinase alpha acts through a double-displacement kinetic mechanism involving enzyme isomerisation, as determined through enzyme and inhibitor kinetics and structural biology===


The entry 4da5 is ON HOLD until Apr 12 2014
==Function==
[[http://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN]] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref>  


Authors: Brown, K., Hudson, C., Charlton, P., Pollard, J.
==About this Structure==
[[4da5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DA5 OCA].  


Description: Choline Kinase alpha acts through a double-displacement kinetic mechanism involving enzyme isomerisation, as determined through enzyme and inhibitor kinetics and structural biology
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Brown, K.]]
[[Category: Charlton, P.]]
[[Category: Hudson, C.]]
[[Category: Pollard, J.]]
[[Category: Cytoplasmic]]
[[Category: Kinase]]
[[Category: Signal transduction]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/4da5"