3n59: Difference between revisions

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[[Image:3n59.png|left|200px]]
<!--
The line below this paragraph, containing "STRUCTURE_3n59", creates the "Structure Box" on the page.
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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{{STRUCTURE_3n59|  PDB=3n59  |  SCENE=  }}  
{{STRUCTURE_3n59|  PDB=3n59  |  SCENE=  }}  
===Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate===
===Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate===
{{ABSTRACT_PUBMED_21410435}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
The line below this paragraph, {{ABSTRACT_PUBMED_21410435}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_21410435}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:021410435</ref><references group="xtra"/>
<ref group="xtra">PMID:021410435</ref><references group="xtra"/><references/>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Snee, W C.]]
[[Category: Snee, W C.]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: 3-dehydroshikimate]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Dehydratase]]
[[Category: Drug target]]
[[Category: Lyase]]
[[Category: Shikimate pathway]]
[[Category: Structural genomic]]
[[Category: Tb structural genomics consortium]]
[[Category: Tbsgc]]
[[Category: Tuberculosis]]

Revision as of 20:44, 17 April 2013

Template:STRUCTURE 3n59

Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate

Template:ABSTRACT PUBMED 21410435

Function

[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]

About this Structure

3n59 is a 24 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002

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