2ybr: Difference between revisions

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[[Image:2ybr.png|left|200px]]
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{{STRUCTURE_2ybr|  PDB=2ybr  |  SCENE=  }}  
{{STRUCTURE_2ybr|  PDB=2ybr  |  SCENE=  }}  
===CRYSTAL STRUCTURE OF THE HUMAN DERIVED SINGLE CHAIN ANTIBODY FRAGMENT (SCFV) 9004G IN COMPLEX WITH CN2 TOXIN FROM THE SCORPION CENTRUROIDES NOXIUS HOFFMANN===
===CRYSTAL STRUCTURE OF THE HUMAN DERIVED SINGLE CHAIN ANTIBODY FRAGMENT (SCFV) 9004G IN COMPLEX WITH CN2 TOXIN FROM THE SCORPION CENTRUROIDES NOXIUS HOFFMANN===
{{ABSTRACT_PUBMED_21489992}}


 
==Function==
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[[http://www.uniprot.org/uniprot/SCX2_CENNO SCX2_CENNO]] Mammal beta-toxins bind voltage-independently at site-4 of sodium channels and shift the activation voltage to more negative potentials. This toxin is active against mammals.  
The line below this paragraph, {{ABSTRACT_PUBMED_21489992}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_21489992}}


==About this Structure==
==About this Structure==
[[2ybr]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Centruroides_noxius_hoffmann Centruroides noxius hoffmann] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBR OCA].  
[[2ybr]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Centruroides_noxius Centruroides noxius] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBR OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:021489992</ref><references group="xtra"/>
<ref group="xtra">PMID:021489992</ref><references group="xtra"/><references/>
[[Category: Centruroides noxius hoffmann]]
[[Category: Centruroides noxius]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Becerril, B.]]
[[Category: Becerril, B.]]

Revision as of 20:55, 17 April 2013

Template:STRUCTURE 2ybr

CRYSTAL STRUCTURE OF THE HUMAN DERIVED SINGLE CHAIN ANTIBODY FRAGMENT (SCFV) 9004G IN COMPLEX WITH CN2 TOXIN FROM THE SCORPION CENTRUROIDES NOXIUS HOFFMANN

Template:ABSTRACT PUBMED 21489992

Function

[SCX2_CENNO] Mammal beta-toxins bind voltage-independently at site-4 of sodium channels and shift the activation voltage to more negative potentials. This toxin is active against mammals.

About this Structure

2ybr is a 9 chain structure with sequence from Centruroides noxius and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Canul-Tec JC, Riano-Umbarila L, Rudino-Pinera E, Becerril B, Possani LD, Torres-Larios A. Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides noxius Hoffmann by a Human-derived Single-chain Antibody Fragment. J Biol Chem. 2011 Jun 10;286(23):20892-900. Epub 2011 Apr 13. PMID:21489992 doi:10.1074/jbc.M111.238410

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